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Clusters of complement-type ligand binding repeats in the LDL receptor family are thought to mediate the interactions between these receptors and their ...
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The binding of ligands to clusters of complement-type repeat (CR)-domains in proteins of the low-density lipoprotein receptor (LDLR) family is dependent on Ca2+ ...
The Low-Density Lipoprotein (LDL) Receptor-related protein 2 (LRP2) or Megalin is a single-pass, transmembrane receptor of the LDL receptor gene family ( ...
Nov 1, 1998 · Although some ligands do not compete with each other, binding of all is uniformly blocked by the 39-kD receptor-associated protein (RAP). RAP is ...
Aug 1, 2005 · The chaperone receptor–associated protein (RAP) blocks all ligand binding to these clusters. ... Disruption of the LRP gene in LDLR knockout mice ...
LRP, like all members of the LDLreceptor gene family, consists of five common structural units shown in Figure 1: (a) ligand-binding (complement) type cysteine- ...
Nov 1, 1998 · 39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/α2-macroglobulin receptor. J Biol Chem. 266.
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A residual binding of both recombinant FVIII variants to the CR doublets non-active for plasma-derived FVIII was attributed to a non- specific component. Also, ...
The low-density lipoprotein receptor-related protein (LRP) is a 600-kD scavenger receptor that binds a number of protein ligands with high affinity.
number of complement-type ... The LDL- receptor-related protein, LRP, is an apolipoprotein E-binding protein. ... protein receptor family, alpha 2-macroglobulin ...